Deadliest Cancer Revealed: Experts Warn Against Major Risk Factor—Alcohol
A new U.S. study links heavy alcohol consumption to pancreatic cancer, one of the most lethal cancers, with survival rates as low as 10% after the first year.
Kokcha News Agency: A groundbreaking study from Florida highlights that regular, high alcohol intake damages pancreatic cells responsible for producing digestive enzymes, leading to inflammation and precancerous lesions. Over time, mutations in the Ras gene (which controls cell growth) and activation of the inflammation-triggering CREB gene can drive cancer development. Researchers suggest blocking CREB could prevent tumor formation.
Key Findings:
- Survival Rates: Only 10% of patients survive the first year post-diagnosis; 1% survive three years.
- Rising Cases: Pancreatic cancer, dubbed the “silent killer,” is increasing among younger adults, though improved imaging may explain part of this trend.
- Symptoms: Unexplained weight loss, fatigue, abdominal pain, jaundice, and bowel habit changes often signal advanced disease.
Types of Pancreatic Cancer:
- Adenocarcinoma (90% of cases): Aggressive, symptomless until late stages.
- Endocrine Tumors: Slower-growing but can become malignant over time.
High-Risk Groups (per UK NHS):
- Adults over 65
- Chronic pancreatitis patients
- Those with family history, diabetes, obesity, or smoking habits
- Individuals consuming processed meats or with specific blood types
- — Kokcha News Agency
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